Respectful dialogue and connection during the conference ‘The 3Rs and NAMs: all inclusive!’
On 19 June, more than 170 people from the various networks of animal testing and non-animal innovation gathered in Media Plaza of the Jaarbeurs in Utrecht. More than 70 people also joined online. Together, we explored the best way forward for human-based biomedical and translational science.
The various sectors were well represented, by researchers working with NAMs (New Approach Methodologies) and 3Rs (Replacement, Reduction and Refinement of animaltesting), participants from the regulatory field, policymakers, NGOs and industry figures. Both national and international networks were represented. The international representation consisted largely of people involved in the IMP3ROVE network.
The COST Action IMP3ROVE also contributes to the 3Rs and NAMs through activities in the field of replacement and the quality of biomedical research by, among other things, increasing reproducibility and translatability.
Young professionals
Many young professionals were also present at the event. Victoria de Leeuw of Young TPI and Felicia van der Fleur of Young DALAS highlighted the importance of mentors, coaches, cheerleaders, friends and peers for the future generation in helping them achieve their personal ambitions in their studies and careers.
Hans Clevers and Thomas Hartung on the role of large companies and AI
The meeting was hosted by Jeffrey Bajramovic (3R Centre Utrecht) and Erica van Oort (TPI) on behalf of the organisers. Hans Clevers was the first keynote speaker. He had an important message: big pharmaceutical companies are engaged in continuous dialogue with regulatory bodies to get NAMs accepted, and that this dialogue is both instructive and necessary. The second keynote speaker, Thomas Hartung, introduced ToxAIcology: the safety testing of substances using ‘big data, big computers and big sense’.
Many questions about NAMs and 3Rs
Lunch was followed by two sessions, with speakers and panel discussions, that yielded multiple questions and insights on 3Rs and NAMs. Are NAMs free from ethical concerns? And what is good validation? How can we help researchers make ethical choices? Do responsible research practices depend on our willingness to change? How does the new Dutch political reality affect the transition to animal testing-free research?
Respectful dialogue
Were the expectations fulfilled? Reflecting on the day, Erica and Jeffrey concluded that there was a strong sense of positivity in the room. The participants were challenged to share their thoughts and join in deliberations, and also to play an active role. The event represented a meaningful advance towards engaging all stakeholders in respectful dialogue.
We thank all the participants for their inspiring, critical and valuable contributions. And we would also like to thank the speakers and panellists for their contributions on stage. Finally, thanks also to Desiree Hoving for enthusiastically and expertly chairing the meeting.
See also our retrospect and photo gallery.